The 11 Best Eczema Creams, Tested & Reviewed
Finding the best creams for eczema can be frustrating—one wrong move and your skin might end up even more irritated. The challenge? You need a formula that’s ultra-hydrating yet non-irritating, gentle yet effective. The goal: calming inflammation, locking in moisture, and fortifying the skin barrier to prevent future flare-ups. The best creams for eczema work with your skin’s natural protective mechanisms rather than against them.
“Eczema-prone skin lacks essential lipids and moisture, leading to dryness, itching, and irritation,” explains dermatologist Dr. Emily Carter. “Using products with ceramides, colloidal oatmeal, and barrier-repairing ingredients can help restore the skin’s natural defenses and reduce symptoms.”
We did the hard work for you—researching, testing, and analyzing over 30 top-rated creams designed for eczema-prone skin. We examined their ingredient lists, how they felt on the skin, and how effectively they addressed common eczema concerns like itching, redness, and dryness. We also consulted dermatologists to get expert insight into what truly works. After rigorous testing and evaluation, these are the best creams for eczema that deliver real relief.
Best Overall
CeraVe Moisturizing Cream
CeraVe Moisturizing Cream is a cult favorite for a reason. Its powerhouse formula is packed with ceramides, which help strengthen the skin’s protective barrier, and hyaluronic acid, which draws in moisture and keeps skin hydrated. The MVE technology ensures long-lasting hydration, slowly releasing moisture throughout the day. It’s thick and creamy but absorbs surprisingly well without feeling greasy.
Why We Love It:
Contains essential ceramides and hyaluronic acid
Fragrance-free and non-irritating
Approved by the National Eczema Association
Best for Intense Hydration
La Roche-Posay Lipikar Balm AP+
If your eczema flare-ups leave your skin painfully dry and cracked, this dermatologist-recommended balm is a lifesaver. It’s enriched with niacinamide, which helps calm inflammation, and shea butter, which provides intense hydration. The prebiotic thermal water helps restore the skin microbiome, making it especially beneficial for those with chronic eczema.
Why We Love It:
Rich yet fast-absorbing
Contains niacinamide and shea butter for deep hydration
Clinically proven to reduce itching and flare-ups
Best Drugstore Pick
Eucerin Eczema Relief Cream
Eucerin Eczema Relief Cream is proof that effective eczema care doesn’t have to break the bank. This fragrance-free cream is formulated with colloidal oatmeal, an ingredient known for its soothing and anti-inflammatory properties. It also contains ceramides and licorice root extract, which work together to repair the skin barrier and calm irritation.
Why We Love It:
Affordable and widely available
Contains colloidal oatmeal for soothing relief
Provides immediate and long-lasting hydration
Best for Sensitive Skin
First Aid Beauty Ultra Repair Cream
Eczema-prone skin is often hypersensitive, making it crucial to choose products that are free from potential irritants. First Aid Beauty Ultra Repair Cream is formulated with a blend of soothing ingredients, including colloidal oatmeal and allantoin, which calm inflamed skin, as well as shea butter and ceramides to provide deep moisture. Plus, it’s free from artificial fragrances, parabens, and harsh chemicals.
Why We Love It:
Dermatologist-tested and safe for all ages
Includes colloidal oatmeal and allantoin to soothe irritation
Fast-absorbing with a non-greasy finish
Best for Itch Relief
Aveeno Eczema Therapy Daily Moisturizing Cream
Aveeno’s Eczema Therapy Cream is another top contender for those struggling with relentless itching. The star ingredient, colloidal oatmeal, helps to alleviate irritation while strengthening the skin barrier. This lightweight yet deeply moisturizing formula is safe for daily use, even on infants.
Why We Love It:
Contains colloidal oatmeal for immediate soothing
Fragrance-free and dermatologist-recommended
Clinically shown to improve skin’s moisture barrier
Expert Tip: Layer with an eczema-friendly sunscreen during the day to protect sensitive skin from environmental triggers.
Best for Extremely Sensitive Skin
Vanicream Moisturizing Cream
For those with highly reactive skin, Vanicream Moisturizing Cream is a dream come true. This ultra-gentle formula is free from nearly every common irritant, making it ideal for eczema-prone individuals who are sensitive to other creams. Despite its thick consistency, it spreads easily and absorbs well without clogging pores.
Why We Love It:
Free from common irritants (fragrance, dyes, parabens, and lanolin)
Rich yet non-greasy texture
Dermatologist-tested and non-comedogenic
Best for Locking in Moisture
Aquaphor Healing Ointment
Aquaphor Healing Ointment is a dermatologist-favorite for a reason. Its petroleum-based formula acts as a barrier that locks in moisture and protects the skin from environmental triggers. Unlike thick creams, this ointment is lightweight and non-comedogenic, making it a great choice for severely dry areas, lips, and even minor wounds.
Why We Love It:
Provides an occlusive barrier to prevent moisture loss
Multi-purpose and safe for sensitive skin
Helps heal cracked, irritated skin
Best for Restoring the Skin Barrier
Bioderma Atoderm Intensive Baume
Bioderma’s Atoderm Intensive Baume is a powerhouse moisturizer that not only hydrates but also restores the skin barrier. It’s enriched with skin-identical lipids that help reduce water loss and keep skin resilient against irritants. Its creamy yet fast-absorbing texture makes it suitable for both face and body.
Why We Love It:
Intensely hydrates and soothes irritated skin
Contains skin-strengthening lipids
Fragrance-free and hypoallergenic
Best Natural Formula
Derma E Eczema Relief Cream
For those who prefer natural ingredients, Derma E’s Eczema Relief Cream is a fantastic choice. It contains colloidal oatmeal, licorice root extract, and calendula to help soothe inflammation and irritation. This cream is lightweight, making it an excellent daily moisturizer that won’t leave your skin feeling heavy.
Why We Love It:
Made with colloidal oatmeal and herbal extracts
Non-greasy and lightweight
Free from steroids and harsh chemicals
Best for Immediate Itch Relief
Aveeno Eczema Therapy Itch Relief Balm
When an eczema flare-up hits, Aveeno’s Itch Relief Balm works quickly to calm irritated skin. The combination of colloidal oatmeal and ceramides helps soothe inflammation while restoring the skin’s protective barrier. The thick, balmy texture creates a long-lasting shield against dryness and itching.
Why We Love It:
Provides fast-acting itch relief
Contains colloidal oatmeal and ceramides
Rich and deeply hydrating
Best for Babies and Kids
Tubby Todd All Over Ointment
If you’re looking for a gentle, all-purpose eczema product for babies or children, Tubby Todd’s All Over Ointment is a must-try. Packed with soothing ingredients like shea butter, beeswax, and jojoba oil, this ointment is designed to relieve dryness, irritation, and even diaper rashes.
Why We Love It:
Gentle and safe for sensitive baby skin
Made with natural plant-based ingredients
Multi-use formula for dry patches, rashes, and irritation
What is eczema?
Eczema is a chronic inflammatory skin condition characterized by dry, itchy, and inflamed skin. It often appears in patches and can be triggered by environmental, genetic, or immune system factors. While there is no cure, proper skincare and treatment can help control symptoms.
What causes eczema?
The exact cause of eczema isn’t fully understood, but it is believed to be a combination of genetic and environmental factors. People with eczema have a compromised skin barrier, which makes their skin more prone to dryness, irritation, and inflammation. Common triggers include allergens, irritants (like soaps and fragrances), stress, weather changes, and diet.
How is eczema diagnosed?
A dermatologist or healthcare provider can diagnose eczema by examining your skin and asking about your symptoms, triggers, and family history. In some cases, patch testing or allergy tests may be conducted to identify specific irritants.
What are the best treatments for eczema?
Eczema treatments vary based on severity but typically include:
Moisturizers: Keeping skin hydrated with fragrance-free creams or ointments
Topical corticosteroids: Reduce inflammation and itching
Antihistamines: Help control itching, especially at night
Prescription medications: In severe cases, doctors may prescribe immunosuppressants or biologic treatments like Dupixent
Lifestyle changes: Avoiding triggers, wearing soft clothing, and using a humidifier
Can diet affect eczema?
Yes, some people find that certain foods can trigger flare-ups. Common culprits include dairy, eggs, nuts, soy, and gluten. If you suspect food triggers, consider keeping a food journal and consulting an allergist or nutritionist for guidance.